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Description

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Specifically, resveratrol inhibits lipid synthesis via suppression of SREBPs, activates sirtuins in concert with AMPK activation, and downregulates the PI3K/AKT/mTOR pathway, ultimately leading to cancer cell apoptosis

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Lipoic acid synthetase then catalyzes sulfuration at positions 6 and 8 of the octanoyl moiety, forming a dihydrolipoyl moiety (R enantiomer)

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Gronwald and Plaisance, 1998): X-SG (the glutathione conjugate) can then be transported into and sequestered by the vacuole (Li et al, 1995

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