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et al., oral administration of Lactiplantibacillus plantarum Y15 to STZ + HFD-induced T2D mice improved fasting glucose, HbA1c, and HOMA-IR levels, reduced pro-inflammatory cytokines (IL-6, TNF-, among others), decreased the abundance of LPS-producing bacteria, and promoted SCFA-producing populations

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Aggregation of these disrupts normal cellular processes, such as protein degradation, resulting in cellular stress and, ultimately, cell death ( 2.2 Mitochondrial dysfunction Mitochondria are necessary for cellular energy, but in neurodegenerative diseases, mitochondrial dysfunction is a major factor in neuronal damage

From this point of view, the role of aging in uterine and endometrial pathologies has been poorly studied