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49 GandelmanM.DansithongW.KalesS.PaulS.MaagG.AoyamaE.et al (2021)

Large scale animal toxicity studies demonstrated that PENAO was as well tolerated as GSAO, suggesting an interesting therapeutic window for this compound

Animal and mechanistic data show reduced neuropathic pain behavior and improved repair biology, with human studies suggesting benefit in diabetic neuropathy (PMID: 29089890