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IGF-1 DES is a 67-amino-acid truncated IGF-1 analog created by deletion of the N-terminal tripeptide, which reduces its binding to IGF binding proteins and increases local tissue bioavailability

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10.3390/ijms21134702 168 TuonoR

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Cagrilintides weekly dosing positions it as a potentially user-friendly therapy for obesity, especially when compared to daily injectables or oral medications that require strict adherence

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doi: 10.1016/j.canlet.2017.04.017 51 ChangMPNormanDC

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