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doi: 10.1158/1541-7786.MCR-16-0028 96 QaiserH.UzairM.Al-RegaieyK.RafiqS.ArshadM.YooW.-K

Receptor Mechanisms: GHRH vs Ghrelin Pathway The fundamental difference between CJC-1295 and Ipamorelin lies in their receptor targets and mechanisms of action: CJC-1295 (GHRH pathway): Binds to GHRH receptors on pituitary somatotroph cells, stimulating the synthesis and release of growth hormone through the cAMP signalling cascade

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