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2-APQC, a small-molecule activator of Sirtuin-3 (SIRT3), alleviates myocardial hypertrophy and fibrosis by regulating mitochondrial homeostasis

It sits at the core of mitochondrial energy production, converting nutrients into ATP

Because of this short half-life, most clinical protocols call for daily dosing or, in some cases, twice-daily dosing to maintain consistent levels in the body throughout the treatment period

Currently, two main theories are widely accepted, including the trigeminovascular system (TGVS) theory and the cortical spreading depression (CSD) theory

This can result in a frozen facial expression or other problems