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These findings are specific to controlled animal models and are used to better understand how NNMT and related pathways influence energy storage and utilization, not to support clinical or therapeutic conclusions

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In a previous report, 2-week administration of pefloxacin (900 mg/kg/day) to rats caused the emergence of tenocytes with round nuclei in Achilles tendons ( Biomechanical examination Biomechanical examination of the rats was performed using a tensile testing machine (MODEL-1310VRW, Aikoh Engineering, Osaka, Japan)

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2022 Apr 1;100(4):skac069

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Therefore, its stimulation of the NO-system is not simple, uncontrolled activation but rather a highly controlled and regulated effect

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By analyzing the failure patterns in cadaveric specimens, researchers can better understand the thresholds at which the ACL can no longer withstand the applied forces

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