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Failure to clear senescent cells also lead to a pro-tumorigenic microenvironment characterized by chronic inflammation because of the SASP 12,25

Even if the solution looks normal after thawing, the molecular damage may be present but invisible

Clinically, the administration of CIT has been correlated with enhancements in endothelial function, arterial compliance, and exercise performance among geriatric populations as well as individuals suffering from metabolic or cardiovascular pathologies (29, 30)