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Why Bro Science Persists Despite Contradictory Evidence Because it is: Simple Familiar Repeated Rarely challenged Most people do not read: Preclinical data Pharmacologic design rationale Human safety studies They repeat what they heard

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The topic modeling themes were generated by combining Non-Negative Matrix Factorization (NMF) and an LLM, in this case, GPT-4o, to identify key topics within the data

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