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The combo is a tool for the plateau, not a mandatory entry point
No genotoxicity, mutagenicity, or organ-specific toxicity was reported at the doses tested in the preclinical safety evaluation
A Perkin Elmer Gene Amp PCR System 9700 was used with the following cycling conditions: 94 C for 3 min, followed by two cycles of 95 C for 30 s, 60 C for 30 s and 72 C for 30 s followed immediately by the two same cycles with an auto-decrement temperature of 1 C until 51 C, and then 20 cycles of 95 C for 30 s, 50 C for 30 s, 50 C for 30 s and final extension at 72 C for 7 min
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A considerable number of microbial species have been confirmed to participate in intestinal immunity, for example, the segmented filamentous bacterium(SFB) in the intestine can induce Th17 cells in the intestinal lamina propria [59, 60]
