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In its resting state, AhR forms a complex with heat shock protein 90 (HSP90), X-associated protein 2 (XAP2), and p23, localized in the cytoplasm
Recently, research has started to emerge related to GLP-1 weight loss drugs, potentially reducing systemic inflammation in the body
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504,505,506 GLP-1 enhances the insulin signaling pathway in the liver by activating the GLP-1R, especially through the phosphorylation of insulin receptor substrates and the activation of the PI3K/Akt signaling pathway, thereby increasing hepatic insulin sensitivity, facilitating glucose uptake and utilization, and reducing hepatic gluconeogenesis
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