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Microneedling is not strictly required, but it dramatically improves results
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Crit Care (2015) 19(1):402.10.1186/s13054-015-1118-z 7 StevenSHausdingMKrller-SchnSMaderMMikhedYStammPet alGliptin and GLP-1 analog treatment improves survival and vascular inflammation/dysfunction in animals with lipopolysaccharide-induced endotoxemia
Early weeks may have more variation
10.1371/journal.pone.0188238 173
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