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Both tirzepatide and semaglutide are FDA-approved, have support from more long-term data, and are already used in real-life settings

doi: 10.1016/j.molmet.2022.101633 73 JastreboffAMKaplanLMFriasJPWuQDuYGurbuzSet al

As a result, some patients report fluctuating tolerance before stabilization occurs

Only use needles that are compatible for use with SEMGLEE, such as BD Ultra Fine 2A Take a new needle and peel off the protective seal (See Figure f)

Only about 40% of patients with early-stage or localized HCC are suitable for potentially curative treatments (surgical resection, liver transplantation, and local radiofrequency ablation) and 20% are suitable for transcatheter arterial chemoembolization (TACE) if in an intermediate stage (Giordano and Columbano, 2014)