Frederick Sanger (1918-2013) sequenced bovine insulin in 1955, identifying its exact amino-acids composition, 2,3 and was awarded with the Nobel Prize for Chemistry in 1958
Whilst GLP-1 receptor agonists are not licensed for treating inflammatory diseases, emerging clinical evidence suggests potential benefits in several conditions characterised by chronic inflammation
Curriculum Development of Human Clinical Trials for the Next Generation of PhD Students and Early Career Researchers in the Medical, Science, Pharmacy and Health Professions
This new avenue has yet to see a standout success, with Orforglipron emerging as a leading contender, showing promising results in blood sugar control and weight management according to clinical trials [14][15]
Acute kidney injury secondary to dehydration is a documented serious adverse event with these medications