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When stomach pressure or inflammation from medication-induced changes irritates the phrenic nerve (which controls the diaphragm), involuntary hiccups can result

This may lead to better glucose control for some, but it increases the risk of hypoglycemia and significant digestive discomfort for others

Your doctor will start you on a low dose and gradually increase it over several weeks

In March 2013, FDA issued a Drug Safety Communication announcing that it was reviewing new research which suggested an increased risk for pre-cancerous cell chances and pancreatitis in patients who took Januvia and other similar type 2 diabetes medications

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