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The overall picture shows a complex scenario with heterogeneous structures resulting from the degree of stability of the final pores, the presence of intermediate structures, and the contribution of external factors (including lipids) that may modulate pore formation

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The review also documented GSHs role in regenerating vitamin E following detoxification of lipid peroxyl radicals, its involvement in the glyoxalase systems detoxification of dicarbonyl stress induced by methylglyoxal and glyoxal, and its regulation of redox signalling through reversible S-glutathionylation of critical protein cysteine residues