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The peak is middle age More than 1 in 5 adults aged 50 to 64 (22%) currently take a GLP-1, against just 4% of adults under 30

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doi: 10.1097/00001756-199602290-00035

Its mechanism of action is based on selective activation of the ghrelin receptor (GHS-R1a), which signals the hypothalamus and anterior pituitary to increase pulsatile GH secretion