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In the SUSTAIN clinical trials, semaglutide OW achieved superior glycemic control and weight loss compared with several other classes of anti-diabetes medications (ADMs) [14,15,16,17,18], including canagliflozin, an SGLT2i [19]

Furthermore, various studies have demonstrated that MT -deficient mice are more vulnerable to oxidative stress-induced cellular and tissue damage as well as non-communicable diseases associated with oxidative stress [6, 114]

Extensive geographic tumor necrosis with a peritheliomatous pattern (viability of neoplastic cells limited to perivascular regions) is a common feature [1]

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