It works by promoting cell proliferation and enhancing protein synthesis, which is what makes it effective for performance and physique optimisation
Published trials are sparse, but a 2023 observational study reported modest additional weight loss (35 lbs over 12 weeks) with combination therapy versus single-agent, though nausea and dizziness occurred in 34% of patients
Accumulating evidence indicates that LA, supplied as a supplement in the diet, may not be used as a metabolic cofactor but instead, elicits a unique set of biochemical activities with potential therapeutic value against a host of pathophysiological insults
Notably, most clinical investigations studied women (1404 female versus 83 male participants), which is expected since estrogen declines after age 30 years, and further estrogen decline with aging represents health challenges, as well as a reduction in QOL [9, 10, 19,20,21,22] and a degradation in the most visible organ of the bodythe skin [9, 10]
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