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The combination of reduced caloric intake from appetite suppression, increased energy expenditure from glucagon receptor activation, and improved metabolic efficiency from GIP pathway activation creates a powerful synergy

If cold sensitivity persists or is accompanied by other symptoms, it's important to discuss this with your healthcare provider

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Archived from the original on 18 June 2025

According to Supriya Rao, MD, gastroenterologist, director of medical weight loss at Lowell General Hospital, and clinical assistant professor at Tufts University School of Medicine, you can take your medication a few hours earlier or later than usual on your regular dosing day without risking any side effects or interfering with the therapeutic benefits of the drug