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An abundance of drug efflux transporters on the blood side of the plexus epithelial cells add to the physical barrier and protection provided by the choroid plexus

Environmental factors, including exposure to carcinogens and fluctuations in hormonal or metabolic pathways, may also play a role

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This genetic insight helps your provider personalize your starting dose and protocol, increasing the likelihood of rapid, sustained results with fewer side effects

In a cross-over design, patients switched between placebo and EGCG treatment after 6 months, allowing further assessment of EGCG's effects