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Acting on two complementary points of the same axis, the two compounds are studied together for a larger, cleaner GH pulse than either produces alone with Ipamorelin chosen specifically because it raises GH with minimal spillover onto cortisol (the stress hormone) or prolactin

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In individuals with nonalcoholic fatty liver disease (NAFLD) and nonalcoholic steatohepatitis (NASH), it is reported that the GLP1RA semaglutide causes a reduction in liver enzyme levels, reduces liver stiffness and improves metabolic parameters [97]

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Blood (2001) 98(5):144855