They added GHK-Cu in concentrations of 10 M to 10 M and measured: Collagen synthesis (by radioactive proline incorporation) Non-collagen protein synthesis Cell proliferation What they found: Stimulation of collagen synthesis by 70 % at the optimal concentration of 10 M (1 nM) The effect was NOT dependent on increased proliferation, fibroblasts increased production per cell Background: GHK without copper had a dramatically weaker effect , Cu is critical Reversibility: After removing GHK-Cu, synthesis returned to baseline Why it matters: This is the fundamental mechanistic study that documented the effect of GHK-Cu on collagen
How semaglutide aids weight loss Semaglutide significantly impacts CNS processes, including satiety, thermogenesis, blood pressure regulation, neurogenesis, and inflammation reduction
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Hair loss and telogen effluvium related to COVID-19: the potential implication of adipose-derived mesenchymal stem cells and platelet-rich plasma as regenerative strategies
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