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S-Adenosyl methionine quantification assay Intracellular SAM levels were quantified with Bridge-It S-Adenosyl Methionine (SAM) Fluorescence Assay (#1-1-1003, Mediomics)

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Recurrence may occur due to invasion of the tumor edge into the bone, difficulty in complete resection due to a tumor with no envelope (15) or multicenter growth