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doi: 10.1038/s44324-024-00033-2 Summary Keywords hypothyroidism, MAFLD, ECM remodeling, HSC, TH signaling, liver fibrosis Citation Wang T, Duan L, Zhao B, Zhang J, Yu Y and Zhao J (2025) ECM remodeling in hypothyroidism-associated MAFLD: mechanisms, clinical relevance, and therapeutic targets