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Glucagon-like peptide-1 receptor agonists are the main ingredients in both GLP-1 injections and oral medications

It can be used in the " cotton compress " method by placing it on a cotton ball and leaving it on the dark areas for several minutes

Fu Y, Li L, Hao S, Guan R, Fan G, Shi C, Wan H, Chen W, Zhang H, Liu G, Wang J, Ma L, You J, Ni X, Yue Z, Xu X, Sun X, Liu X, Yuen Lee SM (2017) Draft genome sequence of the Tibetan medicinal herb Rhodiolacrenulate

Arthritis Care Res 69(9):13311339 Dai Z, Niu J, Zhang Y, Jacques P, Felson DT (2017b) Dietary intake of fiber and risk of knee osteoarthritis in two US prospective cohorts

People participating in clinical trials tolerated the medication well, although some did experience mild reactions