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Description

It is synthesized primarily in the liver, though individual cells can help regulate their own intracellular glutathione levels based on metabolic need

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Under type 2 (T2) conditions (IL-13 stimulation), human airway epithelial cells (HAECs) generate oxidized phospholipids under control of the 15 lipoxygenase 1 (15LO1) enzyme and its binding with phosphatidylethanolamine-binding protein 1 (PEBP1) (6)

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