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Other outcomes included major adverse cardiovascular events (MACE) (cardiovascular mortality, all-cause mortality, stroke, and myocardial infarction), changes in metabolic parameters, and adverse events

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This type of database analysis allows us to get a glimpse at those longer-term outcomes. The study also included a range of GLP-1based medications, from earlier agents such as liraglutide to newer therapies including semaglutide and tirzepatide

By 12 weeks, the placebo effect appeared to diminish in the placebo group, while the treatment group continued to show improvement