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Pre-existing depression/anxiety increases vulnerability

Secondly, we did not have access to hepatic tissues in subjects, and cannot definitely rule out that there may be some dietary influence on flavin monooxygenasedependent conversion of TMA to TMAO

Elevation in the levels of oxidising molecules during oxidative stress disrupts the functioning of biological systems by extracting electrons from essential organic molecules, ultimately leading to cell damage and death due to ROS toxicity

Given the central role of mitochondria in cellular metabolism and survival, mitochondrial health was also investigated