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And here is something most people miss: aged cells generate more reactive oxygen species, and since melatonin acts as a potent endogenous antioxidant, the body consumes more of it to neutralize oxidative stress

[DOI] [PMC free article] [PubMed] [Google Scholar] Vermoote M

The discovery of glutathione peroxidase by Mills in 1957 was the turning point

Supplementing glycine and N-acetylcysteine (GlyNAC) in older adults improves glutathione deficiency, oxidative stress, mitochondrial dysfunction, inflammation, physical function, and aging hallmarks: A randomized clinical trial

Targeting Tyrosinase in Hyperpigmentation: Current Status, Limitations and Future Promises