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Berberine, an alkaloid extracted from traditional Chinese medicine, binds to the bitter taste receptor TAS2R38 and activates the PLC signaling pathway to stimulate GLP-1 secretion in STC-1 cells [193]

Vogel, H

These findings implicate CHAC2 in various cellular functions, including DNA replication and repair, cell cycle regulation, apoptosis, and stem cell differentiation, indicating that its functional repertoire is more versatile than initially presumed (Peng et al., 2023