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Oxidative stress is one of the several causes of conditions, including diabetes, arthritis, and cancer

The supporters of coffee enemas often tout the antioxidant or anticancer properties of coffee enemas by claiming the cafestol palmitate in coffee promotes glutathione S-transferase, which detoxifies the products of tumour cell metabolism, and that the enema fluid stimulates movement of the colon and drainage of toxic substance from the gut

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Neutralisation of reactive oxygen species

(1990) Does N-acetylcysteine increase the excretion of trace metals (calcium, magnesium, iron, zinc and copper) when given orally