While some individuals may be able to switch to a lower maintenance dose after achieving their weight loss goals, completely stopping treatment typically leads to a reversal of the progress made
ISRN Biochem
Bettenworth D, Buyse M, Bhm M, Mennigen R, Czorniak I, Kannengiesser K, et al
In June 2025, a large study of older adults with Type 2 diabetes found those who took a GLP-1 drug mostly semaglutide had a "substantially higher risk" of developing wet age-related macular degeneration, a rare type of the disease, than people with diabetes who didn't take the medication
Stress management techniques such as mindfulness, relaxation exercises, or cognitive behavioural therapy for insomnia (CBT-I) may be helpful if anxiety or sleep disturbance is contributing to your symptoms