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These advances will rely heavily on the integration of organ-on-chip platforms and digital twin models, enabling continuous in vitro and in silico validation of therapeutic decisions before patient application

All participants were informed about experimental procedures, the purpose of the study, and potential risks before giving written consent

they can offer additional training or see if an alternative therapy exists

Further in vitro analysis revealed GHK-Cus capacity to attenuate the release of key pro-inflammatory cytokines

For studies reporting outcomes at different follow-up periods, the longest available follow-up data were extracted