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Some data suggest improved blood flow and tissue perfusion, potentially via nitric-oxidemediated vasodilation, although effects on skeletal-muscle angiogenesis remain speculative ( Concerns have also been raised about safety in specific stress settings, including increased mortality in certain models of septic shock and other severe inflammatory states ( Animal studies of physical performance Animal data supports Meldonium's therapeutic role in preventing cell damage and preserving function during extreme hypoxic ( For example, a 2017 study by Voronina et al
doi: 10.1007/s00223-021-00911-7 123 AtarashiKTanoueTShimaTImaokaAKuwaharaTMomoseYet al
Merck Research Laboratories
In the morning, each participant filled out a Hangover Symptom Scale questionnaire, evaluating each hangover symptom (feeling thirsty or dehydrated, feeling more tired than usual, headache, nauseated, vomited, feeling weak, difficulty concentrating, more sensitive to light and sound than usual, sweating more than usual, had trouble sleeping, feeling anxious, feeling depressed, experienced trembling or shaking) on a 5 point Likert scale with 1 representing Strongly Disagree and 5 representing Strongly Agree
