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The acetyl moiety prevents the thiol group from oxidizing before absorption, shields the molecule from -GT-mediated hydrolysis in the intestinal lumen, and increases lipophilicity facilitating passive diffusion across intestinal epithelium and cell membranes

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The total radioactivity excretion in mixed bile samples collected between 0 and 72 h was low, and tritium water was primarily detected, accounting for 91.2% (females) and 91.0% (males) of the sample