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Myth: Copper peptides cause permanent skin damage Fact: No credible evidence supports this claim

ROS and RNS may trigger programmed cell death, e.g., apoptosis [29], necessary for tissue remodeling during the development and normal tissue turnover [30], proliferation, differentiation, maturation of neural stem cells, dendritic processes, and synaptic plasticity [31,32,33]

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Statements Author contributions AS: Conceptualization, Methodology, Resources, Writing original draft, Writing review & editing

Start with pea-sized amounts every third night for the first week, then every other night, gradually building to nightly use over 4-6 weeks to minimize irritation