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A common contrast therapy protocol is 15 minutes in a sauna followed by 23 minutes in a cold plunge, repeated two to three times

The ENS afferent fibers innervating the intestinal mucosa are derived mainly from primary intrinsic afferent neurons which form synapses with intestinal epithelial cells and EECs [7]

Due to accumulation of metabolic intermediates, impaired carnitine biosynthesis, reduced protein intake, and increased removal of carnitine through hemodialysis (HD), patients who undergo routine HD usually present with plasma carnitine insufficiency [54]

doi:10.1007/s12011-023-03782-1