Senthelal, S., Li, J., Ardeshirzadeh, S., & others
Vitamin B12 is important for nerve cells, energy production and red blood cell production
In animal-model work, NNMT inhibition with 5-Amino-1MQ has been associated with changes in adipose-tissue mass, in NAD+ pool sizes (because NNMT consumes nicotinamide that would otherwise feed the NAD+ salvage pathway), and in methyl-donor dynamics (because NNMT consumes S-adenosylmethionine)
Researchers who dont verify sourcing risk introducing batch-to-batch inconsistency into their work, which can undermine reproducibility a foundational requirement in scientific research
It may be helpful to take dietary supplements as part of a broader treatment plan, especially if you are deficient in B-12, but they shouldnt be taken as a replacement for therapy, medication, or other evidence-based treatments