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*Correspondence: Mohammed Alsafran, [email protected] This article was submitted to Plant Nutrition, a section of the journal Frontiers in Plant Science Disclaimer All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers

The benefits may vary among individuals, and consistent medical supervision is recommended for safe and effective results

Funding This research was financed by the Dutch Research Council (NWO) domain Applied and Engineering Sciences (TTW) (Project number 15494)

The angle between the hybrid and I domain showed a very moderate ~2 increase for the first 30 ns of simulation time, which eventually dropped to its original angle of ~82

95% CI, 0.60 to 0.91) and 46% reduction (HR, 0.54