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This precautionary recommendation aims to ensure contraceptive efficacy during periods when gastric emptying may be most significantly affected

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Hypoglycemia Inform patients that the incidence of hypoglycemia is increased when linagliptin is added to a sulfonylurea or insulin and that a lower dose of the sulfonylurea or insulin may be required to reduce the risk of hypoglycemia [see Warnings and Precautions (5.3)]

Recent clinical observations suggest that semaglutide-based weight loss therapy may reduce hot flash frequency and intensity by stabilizing body weight and improving metabolic health during this vulnerable transition