Chetan Ahya: So, Seth, there are two relevant points here from Asia supply chain perspective, particularly the tech sector
Evidence specifically examining creatine during pharmacologically assisted weight loss is limited, but the physiological rationale for its use in this context is scientifically plausible
In several cohorts, an annual conversion rate of 510% has been described, with a similar behavior for reversion to states of normoglycemia.8 A recently published registry from China analyzed the prognosis of different subgroups of patients with preDM and different degrees of CKD, finding a higher risk of progression to DM in those with both diseases, preDM and CKD
Recognizing this distinction can shift the approach from frustration to strategy and from not working to working well
Age-related changes in renal function, hepatic metabolism, and tissue perfusion theoretically could influence peptide clearance and distribution, though no studies have systematically examined age effects