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Yet, individuals with pre-existing conditions may be at increased risk of serious adverse effects (including death) if one considers the possibility that large doses of supplemental vitamin E might interfere with medications, and possibly lower their efficacy or increase their toxicity (1)

90 Taken together, these findings indicate that autophagy is involved in the occurrence and development of UC and that the inhibition of autophagy could be a therapeutic strategy for treating UC by alleviating intestinal inflammation

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doi: 10.1093/jn/134.3.489 12