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Indicatively, BPC 157 induced a NO-release of its own [49,67,68] and therefore counteracted both NO-synthase (NOS) inhibition (i.e., N(G) nitro-L-arginine methylester (L-NAME) hypertension and pro-thrombotic effects) and NO overstimulation (L-arginine hypotension and anti-thrombotic, pro-bleeding effects) [49,67,69]

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L-ergothioneine, an amino acid comprising histidine and a sulfur atom, was first identified by French pharmacist Charles Tanret in rye ergot ( Claviceps purpurea ) in 1909

Not a direct replacement for BPC-157

Then, the frequency can be reduced as the patient gets better