71 Jamalian et al 72 observed that myo-inositol (2 g) with 200 ug folate twice a day compared to the metformin group significantly improved BDI and DASS scores in women with polycystic ovary syndrome (PCOS) after 12 weeks of supplementation
Peptides studied in metabolic medicine include GLP-1 analogs, MOTS-C, and others involved in mitochondrial function, appetite regulation, and immune signaling.
It is a medical question, so treat it like one
Some of these adverse effects reported were Toxic Epidermal Necrolysis (a rare but life-threatening skin condition characterized by painful blisters and large areas of skin peeling), air embolism, thyroid dysfunction, and liver, kidney, and neurologic toxicity (The dark side of skin lightening- PubMed) With the proliferation of med-spas in an unregulated fashion, there is a risk of inadequately trained or untrained people giving IV injections in a non-sterile way, which can lead to sepsis and transmission of infections like HIV and hepatitis
While glutathione is naturally made by the body, its safety in supplement form hasnt been established for pregnant women due to limited clinical trials