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Storage instructions vary by medication

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Active secretion of organic acid metabolites in the renal proximal tubules alsoenhances excretion.UGT1A1 MRP2 hepatic transporter Neonates often have immature levels of glucuronidation, thus unconjugated hyperbilirubinemia. Gunn rat which lacks UGT1*1 also develops unconjugated hyperbilirubinemia. Simple bile duct blockage usually causes increase conjugated bilirubin