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Results We describe parenteral administration of OHCbl using a subcutaneous catheter together with a portable infusion pump in a home therapy setting in four pediatric patients with remethylation disorders, two patients with cblC, one patient with cblG, and one patient with cblE deficiency, in whom intramuscular injections were not or no longer feasible

I've used up ampoules that are long out of date and have been subjected to fluctuating heat (terrible for wine!) due to being in my car, etc, and haven't noticed any difference

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One study showed NR at 300 mg/day increased human blood NAD+ ~50% after 8 weeks, whereas higher doses (1000 mg/day) roughly doubled NAD+ levels

In women specifically, higher B12 levels correlate with enhanced athletic performance