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A chamber with more collagen is not the same as a demonstrated improvement in a human condition, and the leap from a molecular or tissue-level change to a meaningful health benefit is exactly the leap that clinical trials exist to test and that has not been made for this route

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, & Carbonero, F

doi: 10.3390/md18110538 91

Before injection, that powder must be dissolved into a liquid carrier and bacteriostatic water is the standard choice because the 0.9% benzyl alcohol in it prevents microbial contamination during the multi-week dosing period