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Assessment of hypertrophy at the tissue level using WGA staining (Figure 3D) revealed increased MCSA in the iron group and substantially reduced myocyte area in the amlodipine-treated group

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Twice-daily dosing is used in some early-phase research protocols to maintain more consistent receptor activation during the initial neuroplasticity induction period, but this approach increases total daily exposure and may elevate the risk of off-target effects