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GPX4 converts GSH into oxidized glutathione (GSSG) and reduces the cytotoxic lipid peroxides (L-OOH) to the corresponding alcohols (L-OH)

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To address this question, we performed an integrated time-resolved analysis of the renal transcriptome and proteome in parallel with the renal and plasma metabolomes in control mice and mice with an induced deletion of Bmal1 in the renal tubule

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